Quadruple therapy for heart failure with reduced ejection fraction of the systemic right ventricle and tricuspid regurgitation in a child
Abstract
Transposition of the Great Arteries (d-TMA) is a congenital heart defect with unrelated lung and systemic circulation. More than 90% of infants die without surgical treatment in the first year of life. Anatomical correction is the “gold standard”, however, atrial switch technique (Mustard or Senning procedure) can be used in selected patients. The long-term result of the atrial switch procedure is characterized by the development of heart failure with a decrease of systemic right ventricular function, tricuspid valve insufficiency, cardiac arrhythmias, etc. These complications may occur in childhood, but medication and its features remain unclear. This paper presents a case of successful quadruple therapy in chronic heart failure with reduced ejection fraction of the systemic right ventricle in a child after Mustard procedure, followed by successful tricuspid replacement.
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