Паллиативная помощь в пульмонологической службе

Sergei N. Avdeev; Galiya S. Nuralieva; Zamira M. Merzhoeva; Natalya V. Trushenko; Stanislav A. Krasovsky; Olga A. Suvorova; Baina B. Lavginova; Julia A. Levina; Diana V. Nevzorova

Avdeev S. N. Sechenov First Moscow State Medical University; Scientific Research Institute of Pulmonology https://orcid.org/0000-0002-5999-2150
Nuralieva G. S. Sechenov First Moscow State Medical University https://orcid.org/0000-0002-4726-4906
Merzhoeva Z. M. Sechenov First Moscow State Medical University https://orcid.org/0000-0002-3174-5000
Trushenko N. V. Sechenov First Moscow State Medical University; Scientific Research Institute of Pulmonology https://orcid.org/0000-0002-0685-4133
Krasovsky S. A. Scientific Research Institute of Pulmonology; Medical and Genetic Research Center named after Academician N.P. Bochkova https://orcid.org/0000-0001-9642-0947
Suvorova O. A. Sechenov First Moscow State Medical University https://orcid.org/0000-0001-9661-7213
Lavginova B. B. Sechenov First Moscow State Medical University https://orcid.org/0000-0003-1254-6863
Levina Yu.A. Sechenov First Moscow State Medical University https://orcid.org/0000-0002-0928-2900
Nevzorova D. V. Sechenov First Moscow State Medical University https://orcid.org/0000-0001-8821-2195

Keywords: cystic fibrosis, palliative care, disease progression, quality of life, respiratory support

Abstract

Despite advances in targeted therapies, cystic fi brosis (CF) remains a severe genetic disease with progressive clinical course, where complications signifi cantly impair patients’ quality of life. Modern approaches to treatment have increased the average life expectancy to 44 years, but there are limitations in the long-term eff ectiveness of targeted therapy and the impact of severe CF on the prognosis of patients. A distinct subgroup comprises patients with progressive CF, defi ned by criteria including FEV1 < 40% predicted, arterial hypercapnia, concomitant pulmonary hypertension, and frequent disease exacerbations. For these patients, early integration of palliative care aimed at improving quality of life, symptom control, and psychosocial support is particularly relevant. Th is review discusses consensus recommendations for incorporating palliative care into standard CF management.

Author Biographies

Avdeev S. N., Sechenov First Moscow State Medical University; Scientific Research Institute of Pulmonology

Academician of the Russian Academy of Sciences, Doctor of Medical Sciences, Professor, Head of the Department of Pulmonology N.V. Sklifosovsky Institute of Clinical Medicine

Nuralieva G. S., Sechenov First Moscow State Medical University

Candidate of Medical Sciences, Associate Professor of the Department of Pulmonology at the N.V. Sklifosovsky Institute of Clinical Medicine

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Palliative care in pulmonology

Abstract

Author Biographies

References