Features of drug therapy in patients with chronic heart failure in real clinical practice (chronic heart failure registry in the Tyumen region)

Keywords: бесшовная помощь

Abstract

In recent years, the capabilities of modern therapy in improving the prognosis of CHF have changed significantly. This is largely due to introduction of new drugs: angiotensin II receptor antagonists with neprilysin inhibitor and sodium glucose transporter type 2 inhibitors.
The purpose of the study was to analyze drug therapy in patients with CHF depending on phenotype, functional class and stage
of CHF who presented in hospitals of the Tyumen region between January 2020 and July 2023. We analyzed data on 7303 patients with CHF class I—IV. Mean age was 69.8±9.8 years. Men comprised 40.6% (n=2962). There were different stages and phenotypes of CHF. The compliance of drug therapy with modern clinical guidelines was estimated. No interventions in management
of patients were expected. Examination and treatment were completely determined by attending physicians.
Despite common use of certain classes of drugs included in optimal drug therapy, there are insufficient prescriptions of quadruple therapy (sodium glucose transporter type 2 inhibitors, angiotensin II receptor antagonists with neprilysin inhibitor, β blockers,
mineralocorticoid receptor antagonists) and individual prescriptions (sodium glucose transporter type 2 inhibitors, otensin II receptor antagonists with neprilysin inhibitor). This can affect further course of CHF in this region.

Author Biographies

Lazareva Natalia Vitalievna, Chazov National Medical Research Center of Cardiology

Leading researcher at the Laboratory for Monitoring Programs to reduce Mortality from Cardiovascular Diseases of the Scientific and Organizational Department, cardiologist of the highest qualification category, Candidate of Medical Sciences In 1994, she graduated from the Siberian Order of the Red Banner of Labor Medical University with a degree in medical treatment, in 1995 she completed her clinical residency in cardiology, and in 2001 she defended her PhD thesis at the Federal State Institution "RCNPC" of the Federal Agency for Health and Social Development. After completing his postgraduate studies, he currently works at the Chazov National Research Medical Center of the Ministry of Health of the Russian Federation. Member of the Russian Society of Cardiology. Co-author of patent No. 2007126871/14(029247) "Method of electrocardiographic diagnosis of left ventricular hypertrophy in overweight patients with hypertension" and co-author of the application of the new medical technology FS No. 2011/092 "The use of complex analysis of orthogonal electrocardiogram leads in the diagnosis of LVH in patients with hypertension". N.V. Lazareva is the author of more than 40 scientific publications.

Airapetian Anna Arturovna, Chazov National Medical Research Center of Cardiology

Laboratory assistant researcher at the Laboratory for Monitoring Programs to Reduce Mortality from Cardiovascular Diseases of the Scientific and Organizational Department, cardiologist In 2020, she graduated from the I.M. Sechenov Moscow Medical Academy with a degree in medicine, and in 2022, she completed her clinical residency in cardiology. After completing his residency, he currently works at the Chazov National Research Medical Center of the Ministry of Health of the Russian Federation. Field of activity: chronic heart failure, remote methods of monitoring health indicators. Member of the Russian Society of Cardiology and the Society of Specialists in Heart Failure. A.A. Hayrapetyan is the author and co-author of scientific publications and reports. Awarded the medal for Courage and valor in the fight against COVID-19

Mezhonov Evgeny Mikhailovich, Tyumen State Medical University; Regional Clinical Hospital No.1

Doctor of Medical Sciences

Sorokin Evgeny Vladimirovich, Chazov National Medical Research Center of Cardiology

Head of the Scientific and Organizational Department, Candidate of Medical Sciences In 1990, he graduated from the I.M. Sechenov Moscow Medical Academy with a degree in medicine, and in 1992, he completed his clinical residency in cardiology. In 1996, he defended his PhD thesis in cardiology and biochemistry. After completing his postgraduate studies, he currently works at the Chazov National Research Medical Center of the Ministry of Health of the Russian Federation. He has been in charge of the Scientific and Organizational Department since 2017. Member of the Russian Society of Cardiology, Society of Specialists in Heart Failure. Co-author of 72 scientific publications. The Hirsch index in RSCI is 18, and in Scopus it is 2. The certificate in the specialty "cardiology" is valid until 02.10.2025. The certificate in the specialty "Healthcare organization and public health" is valid until 12/30/2024. He was awarded Honorary diplomas of the Institution and the gratitude of the Minister of Health of the Russian Federation.

Prints Julia Shamilevna, Regional Clinical Hospital No.1, Tyumen, Russia; 5 Department of Health of the Tyumen Region

Head of Cardiology Department No. 3, cardiologist, anesthesiologist, intensive care physician, functional diagnostics doctor, highest qualification category, Chief freelance cardiologist at the Tyumen Region Department of Health, member of the Russian Society of Cardiology, experience of 14 years.

Osmolovskaya Julia Failevna, Chazov National Medical Research Center of Cardiology

Head of the 8th Clinical Department, cardiologist of the highest qualification category, Candidate of Medical Sciences In 2003, she graduated from the Pirogov Russian State Medical University with a degree in medicine, and in 2005, she completed her clinical residency in cardiology at the Federal State Institution RCNPC of the Federal Agency for Health and Social Development. He is a member of the Expert Center on Cardiac Amyloidosis of the Chazov National Research Medical Center of the Ministry of Health of the Russian Federation. She was awarded a diploma from the Federal State Budgetary Institution "NMITSK named after Academician E.I. Chazov" of the Ministry of Health of the Russian Federation. The results of scientific activity of Yu.F. Osmolovskaya is represented in more than 50 publications. The Hirsch index in the RSCI is 8.

Zhirov Igor Vitalievich , Chazov National Medical Research Center of Cardiology; Russian Medical Academy of Continuous Professional Education

Doctor of Medical Sciences, Leading Researcher at the Department of Myocardial Diseases and Heart Failure of the Chazov National Research Medical Center of Cardiology of the Ministry of Health of the Russian Federation, Professor at the Department of Cardiology of the Russian Ministry of Health. 12 In 1997, he graduated from the I. M. Sechenov Moscow Medical Academy, and in 1999, he completed his clinical residency in cardiology at the Peoples' Friendship University of Russia. 1 He is the director of the National Society for the Study of Heart Failure and Myocardial Diseases, a member of the working group on Myocardial and Pericardial Diseases of the European Society of Cardiology, a member of the Expert Center on Cardiac Amyloidosis of the Chazov National Research Medical Center of the Russian Ministry of Health. 2 He was awarded the badge "Excellent Healthcare Worker" (2016). 1 Co-author of 5 monographs, 3 textbooks, 2 patents for inventions, 110 publications.

Tereshchenko Sergey Nikolaevich, Chazov National Medical Research Center of Cardiology

Head of the Department of Myocardial Diseases and Heart Failure, Head of the Expert Center on Cardiac Amyloidosis, Professor, Doctor of Medical Sciences, Honored Scientist of the Russian Federation In 1984 he graduated from the I.M. Sechenov MMA. The results of S.N. Tereshchenko's scientific activity are presented in more than 600 publications. He has edited 3 foreign monographs, 16 chapters in books and manuals, 11 teaching aids, and 4 inventions. S.N. Tereshchenko is actively engaged in teaching, and a new scientific school has been established under his leadership. This is reflected in the subject matter of the defended 7 doctoral and 22 candidate theses. S.N. Tereshchenko's students carry out extensive scientific work, occupy leading positions, including the chief specialists of the Ministry of Health of Russia and various subjects of our country. Professor S.N. Tereshchenko is Chairman of the Board of the National Society for the Study of Heart Failure and Myocardial Diseases and the Board of the Society of Specialists in Emergency Cardiology, member of the Board of the Russian Society of Cardiology, member of the European Working Group on Emergency Cardiology. He was awarded a diploma from the Ministry of Health of the Russian Federation. The Hirsch index in RSCI is 38, and in Scopus it is 21.

Boytsov Sergey Anatolyevich , «Национальный медицинский исследовательский центр кардиологии им. акад. Е.И. Чазова»; Министерство здравоохранения Российской Федерации

Director General of the Chazov National Research Medical Center of the Ministry of Health of the Russian Federation, Chief freelance Cardiologist of the Ministry of Health of the Russian Federation for the Central, Ural, Siberian and Far Eastern Federal Districts, Donetsk People's Republic and Lugansk People's Republic, Academician of the Russian Academy of Sciences, Professor, Doctor of Medical Sciences, Honored Doctor of the Russian Federation

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Published
2025-03-10
How to Cite
Lazareva , N., Airapetian , A., Reitblat , O., Mezhonov , E., Sorokin , E., Prints , J., Osmolovskaya , J., Zhirov, I., Tereshchenko , S., & Boytsov , S. (2025). Features of drug therapy in patients with chronic heart failure in real clinical practice (chronic heart failure registry in the Tyumen region). Russian Cardiology Bulletin / Kardiologicheskii Vestnik, 19(4 часть 1), 72-79. Retrieved from http://ojs2.rucml.ru/index.php/ms-cardiovest/article/view/612
Issue
Vol. 19 No. 4 часть 1 (2024)
Section
Original articles