EFFICIENCY OF DIFFERENTIATED APPROACH TO THE TREATMENT AND PREVENTION OF DISORDERS OF ENDOTHELIAL FUNCTION IN WOMEN WITH SURGICAL AND NATURAL MENOPAUSE

  • E.А. Kolbasova Educational Establishment “Vitebsk State Medical University”
  • N.I. Kiseleva Educational Establishment “Vitebsk State Medical University”
Keywords: menopause, endothelial dysfunction, endothelioprotective medicines

Abstract

The purpose of the study – to evaluate the effectiveness of a differentiated approach to the treatment and prevention of disorders of endothelial function in postmenopausal women. 54 patients have been treated in the period of post-menopausal women: 39 women (I group) using a combined therapy, including endothelioprotective drugs and 15 women (II group) with the use of conventional therapy. Combined therapy led to decrease in the median values of the number of circulating endothelial cells in women in group I 1.8 times, increase in content of nitrate/nitrite in the blood plasma of 1.6 times and to the increase in endothelium-dependent vasodilation of the brachial artery by 1.9 times, that indicates an improvement of the endothelium state against the therapy.

Published
2015-08-04
Issue
No. 3(43) (2013): Journal of the Grodno State Medical University
Section
ORIGINAL STUDIES